If you, for example, go on vacation, it is possible to activate an autoresponder from the control panel, which sends a notification message of your choice to those who contact you via email.
Here's how to activate it:

1. Select the correct server, which will be the one where your email is located, and use your email account information:
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2. Log in.

3. Click on "Modify email account settings" and then navigate to "Autoresponder" on the page that opens.

(Alternative method: Email Accounts -> Click on the email address -> Autoresponder.)

NOTE: This is only a test domain, but the setup is done this way.

4. Click OK when you are satisfied. After that, it will be in effect.